Warriors vs. Lakers Predictions, Odds & Stats – Oct. 21

The Golden State Warriors square off against the Los Angeles Lakers as just 2.5-point favorites in the first game of the 2025-26 NBA season for both teams on Tuesday, October 21, 2025 at 10 p.m. ET on NBC/Peacock.

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Warriors vs. Lakers Predictions for Tuesday

Our computer projection model for this matchup predicts a final tally of Lakers 112, Warriors 111.

  • Moneyline Pick: Lakers (+125)
  • Total Pick: Under 226 (computer predicts 223.5 points)
  • Pick ATS: Lakers (+2.5)

Recent Warriors vs. Lakers Matchups

Warriors vs Lakers (Recent Matchups)
Date Favorite Spread Total Favorite Moneyline Underdog Moneyline Result
4/3/2025 Lakers -1.5 230.5 -114 -105 123-116 GS
2/6/2025 Lakers -6.5 224.5 -260 +210 120-112 LAL
1/25/2025 Lakers -1 218.5 -113 -106 118-108 LAL
12/25/2024 Warriors -3.5 219.5 -164 +139 115-113 LAL

Warriors 2024-25 Betting Trends

  • Golden State's record against the spread last season was 42-40-0.
  • The Warriors' ATS record as 2.5-point favorites or more was 23-28 last year.
  • Golden State had 41 of its 82 games go over the point total last season.
  • The Warriors were the moneyline favorite 55 total times last season. They went 37-18 in those games.
  • Golden State had a record of 32-17 when playing as a moneyline favorite with odds of -150 or shorter last year (65.3%).

Lakers 2024-25 Betting Trends

  • Los Angeles won 45 games against the spread last year, while failing to cover or pushing 37 times.
  • Against the spread, as underdogs of 2.5 points or greater, the Lakers went 15-14 last year.
  • A total of 41 of Los Angeles' games last year hit the over.
  • The Lakers were underdogs in 33 games last season and won 15 (45.5%) of those contests.
  • Last season, Los Angeles won nine of its 26 games, or 34.6%, when it was the underdog by at least +125 on the moneyline.

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Warriors vs. Lakers Injury Report

Warriors

Warriors:

De'Anthony Melton: Out (Knee),

Moses Moody: Out (Calf)

Lakers

Lakers:

LeBron James: Out (Nerve)

Warriors vs. Lakers Game Time and TV Channel

  • Game day: Tuesday, October 21, 2025
  • Game time: 10 p.m. ET
  • TV channel: NBC/Peacock
  • Location: Los Angeles, California
  • Arena: Crypto.com Arena
  • Live stream: Watch this game on Fubo (Regional restrictions may apply)

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